英文名稱: Anti-GSKIP rabbit polyclonal antibody
別 名: GSK3B interacting protein; HSPC210; C14orf129
抗 原: GSKIP
儲(chǔ) 存: 冷凍（-20℃）
宿 主: Rabbit
反應(yīng)種屬: Human, Mouse, Rat
相關(guān)類別: 一抗
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GSKIP |
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Immunogen: |
Fusion protein of human GSKIP |
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Full name: |
GSK3B interacting protein |
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Synonyms: |
HSPC210; C14orf129 |
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SwissProt: |
Q9P0R6 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
30-150 |
